1.) Right
click the OneDrive for Business icon in the Windows notification area at
the bottom of your screen, and then click Stop syncing a folder…
NOTE: If the OneDrive for
Business icon isn't visible, click the Show
hidden icons button
in the notification tray.
2.) Select the folder you want to stop syncing, and then click Stop syncing.
3.) Click Yes to agree to permanently stop syncing the folder, and then click OK.
4.) Click OK on the next window to acknowledge the actions and make note of the file path
5.) Once you are certain you will not need any of the local files you can delete the folder from within your SharePoint directory (the path is indicated in the acknowledgment in Step 4.